Skip to content
Draft
Show file tree
Hide file tree
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension


Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
1 change: 1 addition & 0 deletions .gitignore
Original file line number Diff line number Diff line change
Expand Up @@ -132,6 +132,7 @@ venv.bak/
# MkDocs build output
docs/site/
public/docs/mavedb/
public/docs/gks-vignettes/

# IDEs and editors
.vscode/
Expand Down
2 changes: 2 additions & 0 deletions docs-gks-vignettes/.gitignore
Original file line number Diff line number Diff line change
@@ -0,0 +1,2 @@
.venv/
site/
14 changes: 14 additions & 0 deletions docs-gks-vignettes/docs/index.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,14 @@
# MaveDB × GA4GH GKS Vignettes

Real-world walk-throughs of how **MaveDB** uses the GA4GH **Genomic Knowledge Standards** to solve core problems in sharing multiplexed assay of variant effect (MAVE) data.

These are drafted for contribution to the [GA4GH GKS Starter Kit](https://github.com/ga4gh/gks-starter-kit); this site is an internal preview. Each vignette is a real implementation — the problem, the data, the tools, and what GKS unlocks — written to be forwardable to a teammate or to leadership.

## The vignettes

- [**Giving every MAVE variant a precise, computable identity with VRS**](vignettes/mavedb-mave-variants-vrs/vignette.md) — mapping every variant into VRS 2.0 as MaveDB's canonical representation. *(VRS · production)*
- [**Annotating a variant once, across every score set that measured it**](vignettes/mavedb-vrs-cross-score-set-harmonization/vignette.md) — the VRS digest as a harmonization key. *(VRS · pilot)*
- [**Carrying a measured variant across every molecular level with Cat-VRS**](vignettes/mavedb-protein-variant-cat-vrs/vignette.md) — a measured variant as a category over its equivalents. *(Cat-VRS · proposal)*
- [**Sharing MAVE functional evidence as computable statements with VA-Spec**](vignettes/mavedb-functional-evidence-va-spec/vignette.md) — study results, functional-impact statements, and pathogenicity statements. *(VA-Spec · production)*

These thread one connected story: the same variants flow from VRS identity, through harmonization and categorization, into VA-Spec evidence.
Loading
Loading